Matthew Perry's Cause of Death Revealed: Acute Effects of Ketamine


Matthew Perry's cause of death has been determined as "acute effects of ketamine," according to the toxicology report released by the Los Angeles County Medical Examiner's Office.

Drowning, Coronary Artery Disease, and Buprenorphine Also Contributed to Perry's Death

The report mentioned additional factors contributing to his death, including drowning, coronary artery disease, and the effects of buprenorphine, a medication used for treating opioid addiction. The manner of death was ruled accidental.

Perry was Undergoing Ketamine Infusion Therapy for Depression and Anxiety

Before his passing, Perry had been undergoing ketamine infusion therapy to address his depression and anxiety. The toxicology report explained that the high levels of ketamine found in his system could have led to cardiovascular overstimulation and respiratory depression, which were the primary lethal effects. According to the Guardian..

On October 28, 2023, authorities responded to a call for a cardiac arrest at Perry's Los Angeles home. He was discovered in a hot tub, and no evidence of foul play or drugs was found at the scene.

Matthew Perry gained widespread recognition for his portrayal of the sarcastic Chandler Bing in the beloved sitcom "Friends" during the 1990s and early 2000s, appearing in more than 200 episodes across ten seasons.

Friends Cast Mourns the Loss of Matthew Perry, Promises to Share More in the Future

Following the news of Perry's death, his "Friends" co-stars, including Jennifer Aniston, Courteney Cox, Lisa Kudrow, Matt LeBlanc, and David Schwimmer, released a statement expressing their profound grief and emphasizing their bond as a family. They requested time to mourn and process the loss, promising to share more in the future. Aniston revealed that she had exchanged text messages with Perry on the day of his passing, describing him as happy and healthy.

Courteney Cox took to Instagram to share a blooper video from the "Friends" set, expressing her gratitude for the moments she shared with Perry and her daily longing for him. Matt LeBlanc also posted on Instagram, reminiscing about their cherished time together and expressing his honor at having called Perry a friend.

Perry's Memoir Revealed Struggles with Addiction and Mental Health

Throughout his career, Perry was candid about his struggles with alcohol and drug addiction, which he addressed in his memoir, "Friends, Lovers, and the Big Terrible Thing," published in 2022. In response to his death, the Matthew Perry Foundation was established to support individuals grappling with addiction, carrying forward Perry's commitment to helping others in need.

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